It will work fine. Yep, just pop the card in, make sure your OS disc is in the drive and follow the on screen instructions. Once the OS is installed pop your mobo driver disc in so it can install the drivers for your network, sound etc. Then restart, plug in your internet and search for Windows updates, while it's doing that you can go to ATI.com and download the drivers for your card. It's going to take a while for Windows to update and get up to speed with the service packs and security upgrades. I and many others on this site use Avast Antivirus, it's free and very effective. I also use Spybot Search And Destroy and Malwarebytes Anti-Malware, the three best free programs that will protect your system. That's all I can think of off the top of my head, if you run into problems tomorrow just drop a line, myself or someone else on here will be sure to help. Good luck.