If you want a paid antispyware program, I suggest either sticking with spyware doctor or getting webroot spyweeper. If you want free Antispy, get ad-aware, spybot s&d and either spywareguard from javacool or spycatcher express from tenebril (for realtime protection as the other two are only on demand scanners).
For antivirus, if you want paid protection, get Kaspersky or NOD32. Trendmicro or Bitdefender aren't bad either.. If you want free AV protection - get AVG, avira, avast or clamwin.